Active Pharmaceutical Ingredients
What is 5-Hydroxytryptophan powder?
5-Hydroxytryptophan (5-HTP) powder is the active ingredient extracted from Griffonia simplicifolia. It is an intermediate product of tryptophan metabolism and belongs to the neurotransmitter class of drugs. It can directly cross the blood-brain barrier and act as a precursor of serotonin (5-hydroxytryptamine).Participate in regulating the functions of the central nervous system such as emotions, sleep and appetite.
COA
| Item | Specification | Result | Testing Method |
|---|---|---|---|
| Product Name | Griffonia Simplicifolia Seed Extract | ||
| Other Name | 5-hydroxytryptophan | ||
| Part Used | Seed | ||
| Assay | |||
| 5-HTP | 98% Min | 98.15% | HPLC |
| Physical & Chemical Control | |||
| Appearance | Off White Fine Powder | Complies | Visual |
| Odor | Characteristic | Complies | Organoleptic |
| Taste | Characteristic | Complies | Organoleptic |
| Sieve Analysis | 100% pass 80 mesh | Complies | 80 mesh screen |
| Loss on Drying | 7% Max. | 4.5% | 5g/100°C/2.5hrs |
| Ash | 9% Max. | 4.3% | 2g/525°C/3hrs |
| Arsenic (As) | 1 ppm Max | Complies | ICP-MS |
| Lead (Pb) | 2 ppm Max | Complies | AAS |
| Mercury (Hg) | 0.2 ppm Max. | Complies | ICP-MS |
| Cadmium (Cd) | 1.0 ppm Max | Complies | ICP-MS |
| Microbiological | |||
| Total Plate Count | 10000 cfu/g Max. | Complies | GB 4789.2 |
| Yeast & Mould | 100 cfu/g Max | Complies | GB 4789.15 |
| Coliforms | Negative | Complies | GB 4789.3 |
| Pathogens | Negative | Complies | GB 29921 |
| Conclusion | Complies with specification | ||
| Storage | In cool & dry place. Keep away from strong light and heat. | ||
| Shelf life | 2 years when properly stored. | ||
| Packing | 25KG/drum, Packed in paper-drums with two plastic-bags inside. |
What is 5-hydroxytryptophan powder used for?
5-hydroxytryptophan has been used in alternative medicine as a possibly effective aid in treating depression.
Other uses not proven with research have included anxiety, down syndrome, alcohol withdrawal, alzheimer disease, headaches, attention deficit disorder, muscle spasms in mouth, fibromyalgia, premenstrual syndrome, seizures, weight loss, parkinson's disease, and sleep disorders.
It is not certain whether 5-hydroxytryptophan powder is effective in treating any medical condition. Medicinal use of this product has not been approved by the FDA. 5-hydroxytryptophan should not be used in place of medication prescribed for you by your doctor.
5-hydroxytryptophan is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.
Other uses not proven with research have included anxiety, down syndrome, alcohol withdrawal, alzheimer disease, headaches, attention deficit disorder, muscle spasms in mouth, fibromyalgia, premenstrual syndrome, seizures, weight loss, parkinson's disease, and sleep disorders.
It is not certain whether 5-hydroxytryptophan powder is effective in treating any medical condition. Medicinal use of this product has not been approved by the FDA. 5-hydroxytryptophan should not be used in place of medication prescribed for you by your doctor.
5-hydroxytryptophan is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.
Is 5-HTP good for ADHD?
Based on the existing research, there are multiple potential functional impairment sites of 5-HT in ADHD, especially in the 5-HT synthesis pathway. This provides a theoretical basis for expanding the research and treatment scope of ADHD, and should not be limited to the traditional focus on dopamine and norepinephrine. However, there are still many limitations in this field at present. For instance, the function of AADC in ADHD is not yet clear, and the relationship between changes in the 5-HT synthesis pathway and ADHD symptoms has not been fully agreed upon. Given the heterogeneity of ADHD, changes in tryptophan metabolism may vary among different patients.
Intervention measures based on 5-HT May be more suitable as adjunctive therapy or treatment for specific symptoms. Future research can further explore the application of tryptophan supplements, 5-HTP supplements, methotrexate, etc. in the treatment of ADHD, and at the same time, conduct in-depth studies on the kynuurine pathway to tap its potential as a biomarker and therapeutic target, which is expected to bring new breakthroughs to the diagnosis and treatment of ADHD.
Intervention measures based on 5-HT May be more suitable as adjunctive therapy or treatment for specific symptoms. Future research can further explore the application of tryptophan supplements, 5-HTP supplements, methotrexate, etc. in the treatment of ADHD, and at the same time, conduct in-depth studies on the kynuurine pathway to tap its potential as a biomarker and therapeutic target, which is expected to bring new breakthroughs to the diagnosis and treatment of ADHD.
Does 5-hydroxytryptophan cause weight gain?
5-HTP (5-hydroxytryptophan) itself does not directly cause weight gain .It is a natural amino acid that can indirectly affect appetite and mood by regulating serotonin levels.Whether it has a significant impact on weight mainly depends on the combined effect of factors such as individual metabolism, dosage, usage cycle and other living habits.
where to buy 5-Hydroxytryptophan powder?
Buy 5-Hydroxytryptophan powder - Contact SoST Biotech Factory for:
✓ Bulk discounts (MOQ 25kg)
✓ FREE 20g samples with COA
✓ OEM services/Specification Customization
Email:ericyang@xasost.com
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Product Data Sheets
| Items | Specification | Results |
| Color | White To light yellow | white |
| Appearance | Powder Or crystal | Powder |
| Oder | Characteristic | Characteristic |
| Total Glucoside Content/% | ≥80 | 85.64 |
| PH | 4.5-7.0 | 5.25 |
| Burned residue/% | ≤1 | 0.09 |
| Loss on Drying/% | ≤6 | 2.45 |
| Pb/(mg/kg) | ≤1 | ＜1 |
| Lead(Pb)/(mg/kg) | ||
| Arsenic/(mg/kg) | ≤1 | ＜1 |
| methanol/(mg/kg) | ≤ 200 | 30 |
| ethanol/(mg/kg) | ≤ 5000 | 1030 |
| Microbiological Analysis： | ||
| TABC | ＜1000cfu/g | ＜1000 cfu/g |
| Yeast/Mold | ＜100 cfu/g | ＜100 cfu/g |
| Shelf Life: | Three Years | |