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What is Ergothioneine Powder?
Ergothioneine powder, an amino acid derived from natural plants that the human body cannot synthesize, exhibits exceptional antioxidant properties. First isolated from ergot fungus by French scientist CharlesTanret in 1909, this compound effectively neutralizes free radicals and plays a vital role in multiple physiological processes. It supports DNA biosynthesis, promotes healthy cellular growth, and enhances immune function.
Spermacetiin is a natural active substance with a variety of physiological functions and broad application prospects, especially in the field of antioxidant and anti-aging.
Spermacetiin is a natural active substance with a variety of physiological functions and broad application prospects, especially in the field of antioxidant and anti-aging.
COA
| Analysis | Description | Testing Result |
| Appearance | White or off-white powder | Complies |
| Identification | HPLC retention time correspond to WRS | Complies |
| Loss on drying | ≤0.50% | 0.06% |
| Ethanol residue | ≤500ppm | 382ppm |
| Heavy metals (Pb) | ≤20ppm | Complies |
| Arsenic(Al2O3) | ≤2ppm | Complies |
| Lead(Pb) | ≤1ppm | Complies |
| Mercury(Hg) | ≤0.2ppm | Complies |
| Cadmium(Cd) | ≤0.3ppm | Complies |
| Total Plate Count | ≤1000 cfu/g | Complies |
| Yeast & Molds | ≤100cfu/g | Complies |
| Coliforms | ≤10 mpn/g | Complies |
| E.coli | Negative in10g | Negative |
| Salmonella | Negative in10g | Negative |
| S.aureus | Negative in10g | Negative |
| Assay | ≥99.0% | 99.40% |
What is the best source of ergothioneine?
Some vegetables, especially those mushroom that are high in ergothione, are excellent sources of ergothione. Examples include boletus (also known as enokitake), oysters, scallops, and shiitakes.

What does ergothioneine do to your body?
Ergothioneine powder directly neutralizes free radicals (such as hydroxyl radicals) and prevents damage to cell membranes and mitochondrial DNA. This effect is more pronounced than glutathione.
It inhibits the NF-κB signaling pathway, reduces inflammatory factors (such as IL-6 and TNF-α), and reduces chronic inflammation (such as arthritis and metabolic syndrome). It can protect neurons and reduce the risk of Alzheimer’s and Parkinson’s disease (Cell Reports, 2020).
Reduces oxidative skin damage caused by UV light and suppresses melanin production (found in some high-end skin care products).May improve mitochondrial function and increase physical endurance (animal studies have shown that it reduces lactic acid accumulation after exercise).
It inhibits the NF-κB signaling pathway, reduces inflammatory factors (such as IL-6 and TNF-α), and reduces chronic inflammation (such as arthritis and metabolic syndrome). It can protect neurons and reduce the risk of Alzheimer’s and Parkinson’s disease (Cell Reports, 2020).
Reduces oxidative skin damage caused by UV light and suppresses melanin production (found in some high-end skin care products).May improve mitochondrial function and increase physical endurance (animal studies have shown that it reduces lactic acid accumulation after exercise).
Does ergothioneine powder have any side effects?
Possible gastrointestinal upset: High doses may cause nausea and diarrhea.
Allergy risk: Some people may be allergic to foods containing ergothioneine, such as mushrooms.
Drug interactions: While there is no definitive information available, it is recommended to consult a doctor before taking antioxidants.
Side effects may occur in people who are not receptive to plants and organisms that produce ergothioneine, and who develop a rejection reaction. The exact amount of intake varies from person to person and should be applied after consulting a professional or doctor.
Drug interactions: While there is no definitive information available, it is recommended to consult a doctor before taking antioxidants.
Side effects may occur in people who are not receptive to plants and organisms that produce ergothioneine, and who develop a rejection reaction. The exact amount of intake varies from person to person and should be applied after consulting a professional or doctor.
Who should not take ergothioneine?
People allergic to mushrooms, people allergic to foods containing ergothioneine powder, people with severe liver and kidney dysfunction, etc., can affect normal diet intake, and high doses should be taken under medical advice.There is no strict group that can not be used, and it should be judged according to whether the individual constitution can adapt.
Where to buy Ergothioneine Powder?
SOST Biotech SC Factory can provide synthetic ergothioneine (99%) and natural ergothioneine powder (Pleurotus eryngii, 1%-5%):
1. Free samples can be provided upon your request.
1. Free samples can be provided upon your request.
2. Production capacity: 20 tons/month.
3. The factory covers an area of 7,000 square meters and has 4 Ph.D. technical engineer.
4. Transportation method: express, air transport, sea transport
5. Quality control: 3rd party laboratory testing by Eurofins, SGS, BV etc.
6. 24 hours and 7 days full time standing-by services.

Product Data Sheets
| Analysis | Description | Testing Result |
| Appearance | White or off-white powder | Complies |
| Identification | HPLC retention time correspond to WRS | Complies |
| Loss on drying | ≤0.50% | 0.06% |
| Ethanol residue | ≤500ppm | 382ppm |
| Heavy metals (Pb) | ≤20ppm | Complies |
| Arsenic(Al2O3) | ≤2ppm | Complies |
| Lead(Pb) | ≤1ppm | Complies |
| Mercury(Hg) | ≤0.2ppm | Complies |
| Cadmium(Cd) | ≤0.3ppm | Complies |
| Total Plate Count | ≤1000 cfu/g | Complies |
| Yeast & Molds | ≤100cfu/g | Complies |
| Coliforms | ≤10 mpn/g | Complies |
| E.coli | Negative in10g | Negative |
| Salmonella | Negative in10g | Negative |
| S.aureus | Negative in10g | Negative |
| Assay | ≥99.0% | 99.40% |
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