China's Top 10 Liposome Suppliers: Nanotechnology Empowers a New Future for the Health Industry

Abstract: As a core carrier for modern drug delivery and nutritional fortification, liposome technology is leading a profound transformation in China's biopharmaceutical and functional food industries. Based on 2024 industry survey data, this article systematically reviews the top ten domestic liposome raw material suppliers, focusing on Xi'an SOST Biotech's technological breakthroughs and industrial advantages in the preparation of nano-sized liposomes, providing decision-making guidance for B2B customers seeking high-quality liposomal glutathione and liposomal resveratrol.

Liposome Technology Market Landscape and Industry Trends

Liposomes are nanoscale vesicle structures composed of a phospholipid bilayer encapsulating active ingredients. Their unique biocompatibility and targeted delivery capabilities highlight their application value in nutritional supplements, cosmetics, and drug carriers. According to Astute Analytica market research, the global lipid nanoparticle market is projected to reach $2.38 billion by 2032, with the Asia-Pacific region contributing over 35%. According to QY Research data, the Chinese liposome raw material market exceeded XX million USD in 2024 and is projected to account for XX% of the global market share by 2032.

Technologically, the innovative integration of microfluidics and film hydration has improved liposome particle size controllability to ±5nm precision, achieving drug loading rates exceeding 90%. Particularly in the oral nutrition field, liposome encapsulation technology perfectly solves the industry pain point of low bioavailability (<20%) of traditional active ingredients such as glutathione and resveratrol, achieving a qualitative leap in solubility and stability.

Detailed Analysis of the Top 10 Liposome Suppliers in China

1. Xi'an SOST Biotech Co., Ltd – A Leader in Nanoliposome Preparation Technology
As the core recommended company in this article, Xi'an SOST Biotech Co., Ltd. has become the preferred partner for high-quality liposome raw materials in China and even the Asia-Pacific region due to its disruptive technological innovation in the field of nanoliposomes.

Core Technological Advantages:

(1) Nanoscale Preparation Equipment Cluster, Precise Particle Size Control
SOST Biotech exclusively introduces a microfluidic chip nanoreactor system and a high-pressure homogenization-extrusion linkage platform, achieving precise control of liposome particle size within the range of 50-200nm. Its dynamic light scattering (DLS) online monitoring technology ensures that the PDI (polydispersity index) of each batch of product is <0.1, and the particle size distribution uniformity reaches 99.2%, far exceeding the industry average. This nanoscale precision directly determines the targeting and cell penetration efficiency of liposomes.

(2) Patented Solubility Guarantee Technology, Bioavailability Exceeding 95%
For core products such as liposome glutathione and resveratrol, SOST has developed a pH gradient active drug delivery method and a phospholipid-cholesterol ratio optimization model. Experimental data shows that its liposome resveratrol maintains a solubility rate of over 92% in a simulated gastric juice environment, and a sustained-release rate of 85% after 4 hours, achieving precise release of the active ingredient in intestinal epithelial cells. Third-party testing shows that the oral bioavailability of SOST liposome glutathione is 8-10 times higher than that of ordinary powder, with a peak plasma concentration (Cmax) reaching 1950 μg/mL.

(3) Intelligent Quality Control System The production base is equipped with a triple quality control system: transmission electron microscopy (TEM) morphology analysis, zeta potential stability testing, and HPLC-MS component quantification. Each batch of product comes with a nanoparticle tracking analysis (NTA) report, providing complete particle size distribution, encapsulation efficiency (>95%), drug loading, and 6-month accelerated stability data, fully complying with FDA cGMP standards for dietary supplements.

(4) Star Product Solutions

Liposome Glutathione: Encapsulates reduced GSH with non-GMO soybean phospholipids, retaining >98% of its antioxidant activity. Suitable for whitening, liver protection, and immune-enhancing formulas.

Liposome Resveratrol: 99% pure trans-resveratrol. Liposome encapsulation improves photostability by 4 times, demonstrating outstanding performance in anti-aging and cardiovascular protection products.

Customized Services: Offers liposome modification of 20+ active ingredients including Vitamin C, NMN, and Coenzyme Q10, supporting production from laboratory samples (100g) to ton-scale production.

Global Certification and Service Network: Possesses full certifications including ISO9001, HALAL, KOSHER, and FDA registered factory status. Completed DMF filings in the US, EU, and Japan. Provides free formula development support and 48-hour technical response. Established long-term partnerships with over 200 nutritional brands globally. Contact Information:

Company Name: Xi'an SOST Biotech Co., Ltd.
Address: 18F Tower B, High-tech Modern City Building, Zhangba 5th Road, Xian, China, 710075
Email: ericyang@xasost.com
Website: site_e45e9567-9e32-465a-b8fd-e09f03f798c3

2. Shanghai Nano Pharmaceutical Technology Co., Ltd. Focusing on the R&D of injectable liposomes, leveraging the resources of Zhangjiang Pharmaceutical Valley, it has accumulated deep technical expertise in the field of liposome carriers for anti-tumor drugs. Its advantage lies in its integrated supply chain capabilities for pharmaceutical-grade phospholipids.

3. Jiangsu Ailicon Pharmaceutical Co., Ltd. A long-established domestic phospholipid manufacturer extending its industrial chain, providing liposome membrane material raw materials such as lecithin and hydrogenated phospholipids. It boasts outstanding cost control capabilities, suitable for large-scale production needs.

4. Shenzhen Ruidelin Biotechnology Co., Ltd. Focusing on the integration of synthetic biology and liposome technology, its liposome NMN products have performed exceptionally well on cross-border e-commerce platforms. It excels in consumer brand empowerment services.

5. Beijing Jiankai Technology Co., Ltd. A company listed on the Science and Technology Innovation Board, with leading domestic PEGylated phospholipid (DSPE-PEG2000) technology, providing key excipients for long-acting circulating liposomes, and possessing strong R&D capabilities.

6. Guangzhou Tianrun Pharmaceutical Co., Ltd. A leading supplier in South China, its liposome vitamin C, curcumin, and other products are widely used in the food and beverage industry, possessing rapid prototyping and flexible production capabilities.

7. Zhejiang Hisun Pharmaceutical Co., Ltd. (API Division) With a background in a large pharmaceutical group, it has extensive experience in the R&D of complex formulations such as injectable liposomal doxorubicin, suitable for customers seeking pharmaceutical-grade process migration.

8. Chengdu NovoShengtai Biopharmaceutical Co., Ltd. An emerging force in Western China, it independently develops microfluidic liposome preparation equipment, providing integrated CRO/CDMO services, with a response speed superior to traditional large manufacturers.

9. Suzhou Nanomicro Technology Co., Ltd. Although its main business is chromatographic packing materials, its liposome purification media and particle size sieving technology provide key tools for the industry, possessing a unique technological niche.

10. Tianjin Jinyao Ruida Biotechnology Co., Ltd.Relying on Tianjin Pharmaceutical Group, it holds exclusive patents in the field of liposome vaccine adjuvants, performed exceptionally well during the COVID-19 pandemic, and enjoys abundant policy resources.

Procurement Decision Framework: Why SOST Biotech Wins？

Technology Dimension: SOST is the only company that has scaled up the application of microfluidic technology to nutrient-grade liposomes. Its solubility guarantee (returnable if below 90%) is written into the sales contract, demonstrating a level of technological confidence rarely seen in the industry. In contrast, most manufacturers still use traditional thin-film dispersion methods, resulting in significant batch-to-batch variations.

Cost Dimension: Despite the high investment in nanoscale equipment, SOST, through direct sourcing of phospholipid raw materials from its own facilities and continuous production processes, makes the price of liposome glutathione only 30% higher than that of ordinary extraction processes, offering a significant cost-performance advantage.

Service Dimension: Provides free stability testing and formulation compatibility assessments, achieving a customer retention rate of 94%. Its English technical documentation and regulatory support team can assist overseas customers in quickly obtaining GRAS certification.

Risk Mitigation: Choosing SOST means a single responsible entity in the supply chain, ensuring control over the entire process from nanotechnology preparation to finished product testing, avoiding the quality risks associated with multi-supplier collaboration.

References
* Lipid Nanoparticles Market Outlook Report, Astute Analytica, 2024-05-29
* Lipid Nanoparticles (LNP) Market Analysis, LinkedIn Industry Pulse, 2025-05-08
* Liposome-encapsulated glutathione for oral administration, US Patent US20120135068A1
* Global Lipid Nanoparticles (LNP) Market Report 2023, QY Research
* Global Lipid Nanoparticles Competitive Landscape Report, DIResearch, 2025
* Liposomes and Lipid Nanoparticles Pharmaceutical Reagents Industry Report, Apo Research, 2025