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What are the side effects of mushroom glucan powder?
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What are the side effects of mushroom glucan powder?

2025-07-23

What are the side effects of mushroom glucan powder?

It is safe at normal doses, but there are three types of people who need to be careful when taking it.


People with sensitive stomachs
Don't take a large spoonful of it for the first time. Try half a teaspoon (about 1 g) with warm water. Some people start to gurgle after half an hour. It is probably because the intestinal flora has been "awakened". Reducing the dosage or taking it after meals can relieve it.

People with fungal allergies
People who are allergic to mushrooms such as shiitake mushrooms and ganoderma lucidum may develop rashes on their skin and even feel tightness in the throat. Stop taking it immediately if a reaction occurs, drink a large glass of warm water, and take an anti-allergic pill if necessary.

Patients with autoimmune diseases
People with "immune hyperactivity" such as lupus erythematosus and rheumatoid arthritis, if you are taking hormones or immunosuppressants, don't add them yourself. Let the attending physician help you evaluate first.


By the way, a reminder: it does not conflict with antihypertensive drugs or hypoglycemic drugs, but it is best to take it two hours apart to avoid affecting the judgment of the efficacy.

mushroom beta glucan

What are the positive effects of glucan powder on health


The reason why mushroom glucan has attracted widespread attention is that it is "bidirectional immune regulation" - it can both enhance low immunity and inhibit excessive immune response. It is specifically reflected in the following five aspects:
Reduce upper respiratory tract infection: A meta-analysis of 13 randomized controlled trials showed that daily supplementation of 35 mg of yeast or mushroom glucan can reduce the incidence of colds by 23% and shorten the course of the disease by 1.4 days.
Assist in regulating blood lipids: 3-6 g of β-glucan per day can reduce LDL-C by 5-10%. Its mechanism is to increase bile acid excretion and reduce cholesterol reabsorption.
Maintain blood sugar stability: Mushroom glucan delays gastric emptying and inhibits α-amylase activity, thereby reducing postprandial blood sugar peaks, which is particularly friendly to patients with type 2 diabetes.
Improve intestinal flora: It can promote the proliferation of bifidobacteria and lactobacilli as a prebiotic, and inhibit harmful bacteria such as Escherichia coli and Clostridium.
Potential anti-tumor: Low molecular weight β-glucan from shiitake mushrooms can activate NK cells and cytotoxic T cells through Dectin-1 receptors. In experiments, the tumor inhibition rate of colon cancer mouse models can reach 42%.
It should be emphasized that mushroom glucan is not a "magic drug". Its effect is mild and needs to be continuously supplemented for 2-4 weeks to be effective. It is suitable as a daily dietary supplement rather than a substitute for medicine.

Where can I buy mushroom glucan? 

Faced with the mixed "reishi mushroom polysaccharide" and "Shiitake mushroom polysaccharide" products on the market, be sure to identify three hard indicators when purchasing:


Ingredient labeling: The label should clearly state "β-(1,3/1,6)-D-Glucan ≥ X%", and a third-party HPLC test report should be attached.
Raw material traceability: High-quality brands usually use the "organic log cultivation + low-temperature enzymatic extraction" process, and the raw materials can be traced back to specific strains and places of origin.
After-sales guarantee: COA, MSDS, stability report and batch samples can be provided, and small-scale, pilot and ton-level supply are supported.mushroom powder manufacturer


If you need a one-stop solution for the whole process of "raw material selection - sample testing - stable supply", you can contact sost directly. As one of the earliest suppliers focusing on the export of mushroom glucan raw materials in China, sost has GMP workshops, SC production licenses and HALAL/KOSHER/ORGANIC triple certifications. It has four series of glucan powders, including shiitake mushrooms, ganoderma lucidum, versicolor and maitake mushrooms. The specifications can be customized from 10% to 98%, and the minimum order is 1 kg, and the fastest delivery is 3 days.